A 'Fall Line' could better we called a 'Waterfall Line' because this is what it is.
In some parts of the world, one part of the Earth's crust has risen above another and rivers now fall over the drop. The most famous fall line is in the eastern part of the United States. Here all rivers either have waterfalls or rapids on them. The most famous waterfall is near Washington, DC, the capital of the USA. Here the falls are known as the Great Falls of the Potomac.
The waterfalls stopped early colonists from getting goods inland using rivers, and kept most people on the coast.